Article No
GTX84151
Specifications
| Application | ICC, IF, IHC, IP, WB |
| Article No | GTX84151 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | 4C2 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | ERK2 antibody [4C2] |
| Supplier | GeneTex |
| Entrez Gene ID | 5594 |
| Gene Symbol | MAPK1 |
| Immunogen | Full length human recombinant protein of human MAPK1(NP_620407) produced in HEK293T cell. |
| Isotype | IgG1 |
| Notes | Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK1. Phosphorylates EIF4EBP1 | required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1 (By similarity). Phosphorylates heat shock factor protein 4 (HSF4) and ARHGEF2. Acts as a transcriptional repressor. Binds to a [GC]AAA[GC] consensus sequence. Repress the expression of interferon gamma-induced genes. Seems to bind to the promoter of CCL5, DMP1, IFIH1, IFITM1, IRF7, IRF9, LAMP3, OAS1, OAS2, OAS3 and STAT1. Transcriptional activity is independent of kinase activity. |
| Product Type | Antibodies Primary |
| Protocol | WB: 1:1000-1:2000. ICC/IF: 1:50-1:100. IHC-P: 1:50. IP: 2ug/500ul. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications. |
| Purification | Affinity Purified |
| Size | 100µl |
| Source / Host | mouse |
| Species Reactivity | dog/canine, human, monkey, rat |
| Storage | 4°C, -80°C |
| UniProt Number | P28482 |
| Product Page Updated | 2024-01-03T10:31:47.950Z |
