Article No
GTX83996
Specifications
| Application | FC, ICC, IF, WB |
| Article No | GTX83996 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | 4H9 |
| Clone Type | monoclonal |
| Concentration | 0.81 mg/ml |
| Conjugation | Unconjugated |
| Description | NSE2 antibody [4H9] |
| Supplier | GeneTex |
| Entrez Gene ID | 286053 |
| Gene Symbol | NSMCE2 |
| Immunogen | Full length human recombinant protein of human NSMCE2 (NP_775956) produced in E.coli. |
| Isotype | IgG1 |
| Notes | E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. Acts as a E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TRAX, and maybe the cohesin components RAD21 and STAG2. SUMO protein-ligase activity is required for the prevention of DNA damage-induced apoptosis by facilitating DNA repair. |
| Product Type | Antibodies Primary |
| Protocol | WB: 1:2000. ICC/IF: 1:100. FACS: 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications. |
| Purification | Affinity Purified |
| Size | 100µl |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C, -80°C |
| UniProt Number | Q96MF7 |
| Product Page Updated | 2024-01-03T10:31:47.950Z |
