Article No
GTX83555
Specifications
| Application | ICC, IF, IHC, WB |
| Article No | GTX83555 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | 4D10 |
| Clone Type | monoclonal |
| Concentration | 0.67 mg/ml |
| Conjugation | Unconjugated |
| Description | SSX2 antibody [4D10] |
| Supplier | GeneTex |
| Entrez Gene ID | 6757,727837 |
| Gene Symbol | SSX2, SSX2B |
| Immunogen | Full-length protein expressed in 293T cell transfected with human SSX2 expression vector |
| Isotype | IgG1 |
| Notes | The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. This gene, and also the SSX1 and SSX4 family members, have been involved in t(X;18)(p11.2;q11.2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. This gene also has an identical duplicate, GeneID: 727837, located about 45 kb downstream in the opposite orientation on chromosome X. [provided by RefSeq, Jul 2013] |
| Product Type | Antibodies Primary |
| Protocol | ICC/IF: 1:100. IHC-P: 1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications. |
| Purification | Affinity Purified |
| Size | 100µl |
| Source / Host | mouse |
| Species Reactivity | human, monkey, mouse |
| Storage | 4°C, -80°C |
| UniProt Number | Q16385 |
| Product Page Updated | 2024-01-03T10:31:47.950Z |
