Article No
GTX83349
Estrogen Receptor alpha
Estrogen Receptor alpha antibody [2B7]
Antibodies Primary
Specifications
| Application | ELISA, IHC, WB |
| Article No | GTX83349 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | 2B7 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | Estrogen Receptor alpha antibody [2B7] |
| Supplier | GeneTex |
| Entrez Gene ID | 2099 |
| Gene Symbol | ESR1 |
| Immunogen | Purified recombinant fragment of human ER-alpha (410-592aa) expressed in E. Coli. |
| Isotype | IgG1 |
| Notes | This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014] |
| Product Type | Antibodies Primary |
| Protocol | WB: 1/500 - 1/2000. IHC-P: 1/200 - 1/1000. ELISA: 1/10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications. |
| Purification | Protein G Purified |
| Size | 100µl |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C, -80°C |
| UniProt Number | P03372 |
| Product Page Updated | 2024-01-03T10:31:47.950Z |
