Purified recombinant fragment of human ERK2 expressed in E. Coli.
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jul 2008]
Mitogen-Activated Protein Kinase 1,Erk,Erk-2,Erk2,Ert1,Mapk2,P42Mapk,Prkm1,Prkm2,P38,P40,P41,P41Mapk,P42-Mapk,Mapk1
WB: 1/500 - 1/2000.*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications., ICC/IF: 1/200 - 1/1000.*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications., IHC-P: 1/200 - 1/1000.*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications., ELISA: 1/10000.*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Protein G Purified
Source / Host
human, mouse, monkey
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4-8ºC. For long-term storage, aliquot and store at -20-8ºC or below. Avoid multiple freeze-thaw cycles.
Substrate / Buffer
PBS, 0.03% sodium azide
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
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