Article No
GTX60463
Specifications
| Application | ELISA, FC, ICC, IF, IHC, WB |
| Article No | GTX60463 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | 5G9 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | BLNK antibody [5G9] |
| Supplier | GeneTex |
| Entrez Gene ID | 29760 |
| Gene Symbol | BLNK |
| Immunogen | Purified recombinant fragment of human BLNK expressed in E. Coli. |
| Isotype | IgG1 |
| Notes | This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012] |
| Product Type | Antibodies Primary |
| Protocol | WB: 1/500 - 1/2000. ICC/IF: 1/200 - 1/1000. IHC-P: 1/200 - 1/1000. FACS: 1/200 - 1/400. ELISA: 1/10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications. |
| Purification | Unpurified |
| Size | 100µl |
| Source / Host | mouse |
| Species Reactivity | human, mouse |
| Storage | 4°C, -80°C |
| UniProt Number | Q8WV28 |
| Product Page Updated | 2024-01-03T10:31:47.950Z |
