Article No
GTX60450
Specifications
| Application | ELISA, ICC, IF, WB |
| Article No | GTX60450 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | 1H2 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | ABCG2 antibody [1H2] |
| Supplier | GeneTex |
| Entrez Gene ID | 9429 |
| Gene Symbol | ABCG2 |
| Immunogen | Purified recombinant fragment of human ABCG2 expressed in E. Coli. |
| Isotype | IgG1 |
| Notes | The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] |
| Product Type | Antibodies Primary |
| Protocol | WB: 1/500 - 1/2000. ICC/IF: 1/200 - 1/1000. ELISA: 1/10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications. |
| Purification | Unpurified |
| Size | 100µl |
| Source / Host | mouse |
| Species Reactivity | human, monkey, mouse |
| Storage | 4°C, -80°C |
| UniProt Number | Q9UNQ0 |
| Product Page Updated | 2024-01-03T10:31:47.950Z |
