Purified recombinant fragment of human CD1A expressed in E. Coli.
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
WB: 1/500 - 1/2000.*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications., ICC/IF: 1/200 - 1/1000.*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications., IHC-P: 1/200 - 1/1000.*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications., ELISA: 1/10000.*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Source / Host
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4-8ºC. For long-term storage, aliquot and store at -20-8ºC or below. Avoid multiple freeze-thaw cycles.
Substrate / Buffer
Ascites, 0.03% sodium azide
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
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