Article No
GTX53462
Application | Activation, Inhibition, Neutralization, WB |
Article No | GTX53462 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
Clone | 6B11 |
Clone Type | monoclonal |
Conjugation | Unconjugated |
Description | VEGF Receptor 2 antibody [6B11] |
Supplier | GeneTex |
Entrez Gene ID | 3791 |
Gene Symbol | KDR |
Immunogen | hVEGFR2 N-terminal fragment (N30-200) |
Isotype | IgG1 |
Notes | Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009] |
Product Type | Antibodies Primary |
Purification | Protein G Purified |
Size | 100µg |
Source / Host | mouse |
Species Reactivity | human |
Storage | 4°C, -80°C |
UniProt Number | P35968 |
Product Page Updated | 2024-01-03T10:31:47.950Z |