Article No
GTX53252
Application | WB |
Article No | GTX53252 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
Clone | 6C15 |
Clone Type | monoclonal |
Concentration | 500 ug/ml |
Conjugation | Unconjugated |
Description | Cathepsin B antibody [6C15] |
Supplier | GeneTex |
Entrez Gene ID | 13030 |
Gene Symbol | Ctsb |
Immunogen | Mouse recombinant protein of Cathepsin B |
Isotype | IgG1 |
Notes | This gene encodes a member of the peptidase C1 family and preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin B light and heavy chains, which can dimerize to generate the double chain form of the enzyme. This enzyme is a lysosomal cysteine protease with both endopeptidase and exopeptidase activity that may play a role in protein turnover. Homozygous knockout mice for this gene exhibit reduced pancreatic damage following induced pancreatitis and reduced hepatocyte apoptosis in a model of liver injury. Pseudogenes of this gene have been identified in the genome. [provided by RefSeq, Aug 2015] |
Product Type | Antibodies Primary |
Protocol | WB: 1:500 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications. |
Purification | Protein A/G Purified |
Size | 100µg |
Source / Host | rat |
Species Reactivity | mouse |
Storage | 4°C, -80°C |
UniProt Number | P10605 |
Product Page Updated | 2024-01-03T10:31:47.950Z |