Article No
GTX52480
Specifications
| Application | IHC, WB |
| Article No | GTX52480 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone Type | monoclonal |
| Concentration | 200 ug/ml |
| Conjugation | Unconjugated |
| Description | MMP14 antibody [9E10] |
| Supplier | GeneTex |
| Entrez Gene ID | 4323 |
| Gene Symbol | MMP14 |
| Immunogen | Human recombinant MMP-14 |
| Isotype | IgG1 |
| Notes | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. [provided by RefSeq, Jul 2008] |
| Product Type | Antibodies Primary |
| Protocol | WB: 1:400 - 1:800. IHC-P: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications. |
| Purification | Protein G Purified |
| Size | 100µg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C, -80°C |
| UniProt Number | P50281 |
| Product Page Updated | 2024-01-03T10:31:47.950Z |
