Article No
GTX50259
4E-BP1 (phospho Thr45)
4E-BP1 (phospho Thr45) antibody
Antibodies Primary
Specifications
| Application | IHC, WB |
| Article No | GTX50259 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone Type | polyclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | 4E-BP1 (phospho Thr45) antibody |
| Supplier | GeneTex |
| Entrez Gene ID | 1978 |
| Gene Symbol | EIF4EBP1 |
| Immunogen | Peptide sequence around phosphorylation site of threonine 45 (S-T-T(p)-P-G) derived from human 4E-BP1. |
| Isotype | IgG |
| Notes | This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008] |
| Product Type | Antibodies Primary |
| Protocol | WB: 1:500-1:1000. IHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications. |
| Purification | Affinity Purified |
| Size | 100µl |
| Source / Host | rabbit |
| Species Reactivity | human, insect |
| Storage | 4°C, -80°C |
| UniProt Number | Q13541 |
| Product Page Updated | 2024-01-03T10:31:47.950Z |
