Article No
GTX42594
Specifications
| Application | ELISA, Inhibition, Neutralization, WB |
| Article No | GTX42594 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | 030-113.7.5.4 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | C7 antibody [030-113.7.5.4] |
| Supplier | GeneTex |
| Entrez Gene ID | 730 |
| Gene Symbol | C7 |
| Immunogen | Purified human C7. |
| Isotype | IgG1 |
| Notes | This gene encodes a serum glycoprotein that forms a membrane attack complex together with complement components C5b, C6, C8, and C9 as part of the terminal complement pathway of the innate immune system. The protein encoded by this gene contains a cholesterol-dependent cytolysin/membrane attack complex/perforin-like (CDC/MACPF) domain and belongs to a large family of structurally related molecules that form pores involved in host immunity and bacterial pathogenesis. This protein initiates membrane attack complex formation by binding the C5b-C6 subcomplex and inserts into the phospholipid bilayer, serving as a membrane anchor. Mutations in this gene are associated with a rare disorder called C7 deficiency. [provided by RefSeq, Nov 2016] |
| Product Type | Antibodies Primary |
| Protocol | Neutralizing/Inhibition: . *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications. |
| Purification | Protein A Purified |
| Size | 100µg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C, -80°C |
| UniProt Number | P10643 |
| Product Page Updated | 2024-01-03T10:31:47.950Z |
