Article No
GTX42343
Application | ELISA, FC, IP |
Article No | GTX42343 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
Clone | 14C2 |
Clone Type | monoclonal |
Concentration | 1 mg/ml |
Conjugation | Unconjugated |
Description | Fas Ligand antibody [14C2] |
Supplier | GeneTex |
Entrez Gene ID | 356 |
Gene Symbol | FASLG |
Isotype | IgG1 |
Notes | This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2014] |
Product Type | Antibodies Primary |
Protocol | FACS: 1/25-1/50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications. |
Purification | Protein G Purified |
Size | 100µg |
Source / Host | mouse |
Species Reactivity | human |
Storage | 4°C, -80°C |
UniProt Number | P48023 |
Product Page Updated | 2024-01-03T10:31:47.950Z |