Article No
GTX42246
Application | FC, IHC, Inhibition, Neutralization, WB |
Article No | GTX42246 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
Clone | AMY10-105.8 (1H7) |
Clone Type | monoclonal |
Concentration | 1 mg/ml |
Conjugation | Unconjugated |
Description | IGF1R antibody [AMY10-105.8 (1H7)] (Low endotoxin, azide free) |
Supplier | GeneTex |
Entrez Gene ID | 3480 |
Gene Symbol | IGF1R |
Immunogen | Purified human placental IGF-I receptor. |
Isotype | IgG1 |
Notes | This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014] |
Product Type | Antibodies Primary |
Protocol | IHC-P: 1/10-1/40. FACS: 1/10. Neutralizing/Inhibition: . *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications. |
Purification | Protein G Purified |
Size | 100µg |
Source / Host | mouse |
Species Reactivity | human |
Storage | 4°C, -80°C |
UniProt Number | P08069 |
Product Page Updated | 2024-01-03T10:31:47.950Z |