Article No
GTX28217-14
CD45RA
CD45RA antibody [MEM-56] (PE-DyLight 594)
Antibodies Primary
Specifications
| Application | FC |
| Article No | GTX28217-14 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | MEM-56 |
| Clone Type | monoclonal |
| Conjugation | PE/DyLight 594 |
| Description | CD45RA antibody [MEM-56] (PE-DyLight 594) |
| Supplier | GeneTex |
| Entrez Gene ID | 5788 |
| Gene Symbol | PTPRC |
| Immunogen | Human thymocytes and T lymphocytes. |
| Isotype | IgG2b |
| Notes | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012] |
| Product Type | Antibodies Primary |
| Protocol | FACS: 4 µl reagent / 100 µl of whole blood or 10⁶ cells in a suspension. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications. |
| Purification | Size-exclusion Chromatography |
| Size | 100test |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C |
| UniProt Number | P08575 |
| Product Page Updated | 2024-01-03T10:31:47.950Z |
