Article No
GTX21904
alpha Synuclein
alpha Synuclein antibody [4B12]
Antibodies Primary
Specifications
| Application | ELISA, IHC, WB |
| Article No | GTX21904 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | 4B12 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | alpha Synuclein antibody [4B12] |
| Supplier | GeneTex |
| Entrez Gene ID | 6622 |
| Gene Symbol | SNCA |
| Immunogen | Recombinant human alpha synuclein produced in E. coli. |
| Isotype | IgG1 |
| Notes | Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016] |
| Product Type | Antibodies Primary |
| Protocol | Dot: Use at a dilution of 1/100 - 1/10000. ELISA: Use at an assay dependent dilution. IHC-P: Use at a dilution of 1/100 - 1/1000. Antigen retrieval is not essential but may optimise staining. IHC-Fr: Use at a dilution of 1/100 - 1/1000. WB: Use at a dilution of 1/100 - 1/10000. Predicted molecular weight: 16 kDa. Optimal dilutions/concentrations should be determined by the end user. |
| Size | 100µl |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C, -80°C |
| UniProt Number | P37840 |
| Product Page Updated | 2024-01-03T10:31:47.950Z |
