Article No
GTX21828
Specifications
| Application | IHC, WB |
| Article No | GTX21828 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | 3A4 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | TIMP2 antibody [3A4] |
| Supplier | GeneTex |
| Entrez Gene ID | 7077 |
| Gene Symbol | TIMP2 |
| Immunogen | BALB/C mice were injected with a synthetic peptide from the N-terminal region of human TIMP-2. |
| Isotype | IgG2a |
| Notes | This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [provided by RefSeq, Jul 2008] |
| Product Type | Antibodies Primary |
| Protocol | IHC-P: 1:25-1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications. |
| Purification | Purified |
| Size | 250µl |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C |
| UniProt Number | P16035 |
| Product Page Updated | 2024-01-03T10:31:47.950Z |
