Article No
GTX20845
Application | IHC |
Article No | GTX20845 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
Clone | KP1 |
Clone Type | monoclonal |
Conjugation | Unconjugated |
Description | CD68 antibody [KP1] (ready-to-use) |
Supplier | GeneTex |
Entrez Gene ID | 968 |
Gene Symbol | CD68 |
Immunogen | Subcellular fraction of human alveolar macrophages. |
Isotype | IgG1 |
Notes | This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008] |
Product Type | Antibodies Primary |
Protocol | IHC-P: . *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications. |
Purification | Purified |
Size | 6ml |
Source / Host | mouse |
Species Reactivity | human |
Storage | 4°C |
UniProt Number | P34810 |
Product Page Updated | 2024-01-03T10:31:47.950Z |