Article No
GTX133736-25
14-3-3
14-3-3 antibody detects 14-3-3 proteins, which in mammals exist in seven isoforms (β, γ, ε, η, ζ, σ, and τ/θ) and have predicted molecular weights of ~28 kDa. 14-3-3 proteins are homo- or heterodimeric adaptors involved in the regulation of various signaling pathways such as mTOR, AMPK, and MAPK.
Antibodies Primary
Specifications
| Application | WB |
| Article No | GTX133736-25 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone Type | polyclonal |
| Concentration | 0.19 mg/ml |
| Conjugation | Unconjugated |
| Control Tissue | 293T , A431 , HeLa , HepG2 |
| Description | 14-3-3 antibody detects 14-3-3 proteins, which in mammals exist in seven isoforms (β, γ, ε, η, ζ, σ, and τ/θ) and have predicted molecular weights of ~28 kDa. 14-3-3 proteins are homo- or heterodimeric adaptors involved in the regulation of various signaling pathways such as mTOR, AMPK, and MAPK. |
| Supplier | GeneTex |
| Entrez Gene ID | 7529 |
| Gene Symbol | YWHAB |
| Immunogen | Recombinant protein encompassing a sequence within the N-terminus region of human 14-3-3 beta. The exact sequence is proprietary. |
| Isotype | IgG |
| Notes | This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq] |
| Product Type | Antibodies Primary |
| Protocol | WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications. |
| Purification | Affinity Purified |
| Size | 25µl |
| Source / Host | rabbit |
| Species Reactivity | human, mouse |
| Storage | 4°C, -80°C |
| Product Page Updated | 2024-01-03T10:31:47.950Z |
