Article No
GTX12120
Application | FC, IHC, MS, WB |
Article No | GTX12120 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
Clone | 44C143 |
Clone Type | monoclonal |
Concentration | 1 mg/ml |
Conjugation | Unconjugated |
Description | TLR8 antibody [44C143] |
Supplier | GeneTex |
Entrez Gene ID | 51311 |
Gene Symbol | TLR8 |
Immunogen | This antibody was developed against a KLH-conjugated synthetic peptide of human TLR8, within amino acids 750-850. |
Isotype | IgG1 |
Notes | The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X. [provided by RefSeq] |
Product Type | Antibodies Primary |
Protocol | WB: 1 - 3 µg/ml. IHC-P: 5 µg/ml. FACS: 0.5 - 1 µg / 10⁶ cells. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications. |
Purification | Protein G Purified |
Size | 50µg |
Source / Host | mouse |
Species Reactivity | human, mouse |
Storage | 4°C, -80°C |
UniProt Number | Q9NR97 |
Product Page Updated | 2024-01-03T10:31:47.950Z |