Article No
GTX10930
Specifications
| Application | EM, FC, ICC, IF, IHC, IP, WB |
| Article No | GTX10930 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone Type | polyclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | PHD2 antibody |
| Supplier | GeneTex |
| Entrez Gene ID | 54583 |
| Gene Symbol | EGLN1 |
| Immunogen | Synthetic peptide made to a C-terminal portion of human PHD2/HIF Prolyl Hydroxylase 2 (between amino acids 350-426) (GeneID 54583). |
| Isotype | IgG |
| Notes | The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3). [provided by RefSeq] |
| Product Type | Antibodies Primary |
| Protocol | WB: 1:500 - 1:2500. FACS: 1:10 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications. |
| Purification | Affinity Purified |
| Size | 100µl |
| Source / Host | rabbit |
| Species Reactivity | human, rat |
| Storage | 4°C |
| UniProt Number | Q9GZT9 |
| Product Page Updated | 2024-01-03T10:31:47.950Z |
