Article No
GTX10826
Specifications
| Application | FC |
| Article No | GTX10826 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | FITC |
| Description | c-Myc antibody [9E10] (FITC) |
| Supplier | GeneTex |
| Entrez Gene ID | 4609 |
| Gene Symbol | MYC |
| Immunogen | Synthetic peptide sequence (AEEQKLISEEDLL) corresponding to the C-terminal region of human c-Myc. |
| Isotype | IgG1 |
| Notes | This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017] |
| Product Type | Antibodies Primary |
| Purification | Size-exclusion Chromatography |
| Size | 50µg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C |
| UniProt Number | P01106 |
| Product Page Updated | 2024-01-03T10:31:47.950Z |
