Article No
GTX01413-pro
Human ACVRL1 protein, His tag (active)
Human ACVRL1 protein, His tag (active)
Enzymes
Specifications
| Accession Number | NP_000011.2 |
| Application | FA |
| Article No | GTX01413-pro |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Conjugation | Unconjugated |
| Description | Human ACVRL1 protein, His tag (active) |
| Supplier | GeneTex |
| Entrez Gene ID | 94 |
| Gene Symbol | ACVRL1 |
| Notes | This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. [provided by RefSeq, Jul 2008] |
| Product Type | Enzymes |
| Protocol | Measured by its ability to inhibit BMP9-induced alkaline phosphatase production by MC3T3-E1 cells. The ED₅₀ for this effect is typically 50-200 ng/ml in the presence of 2 ng/ml of recombiant human BMP9 protein. |
| Size | 100µg |
| Storage | -20°C |
| UniProt Number | P37023 |
| Product Page Updated | 2024-01-03T10:31:47.950Z |
