Article No
GTX00678
p53 (phospho Ser315)
p53 (phospho Ser315) antibody [#18]
Antibodies Primary
Specifications
| Application | ELISA, ICC, IF, IHC, WB |
| Article No | GTX00678 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | #18 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | p53 (phospho Ser315) antibody [#18] |
| Supplier | GeneTex |
| Entrez Gene ID | 7157 |
| Gene Symbol | TP53 |
| Immunogen | Synthetic peptide containing phospho-Ser315 of p53 |
| Isotype | IgG2b |
| Notes | This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016] |
| Product Type | Antibodies Primary |
| Protocol | WB: 1:1000-1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications. |
| Purification | Purified |
| Size | 100µg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C, -80°C |
| UniProt Number | P04637 |
| Product Page Updated | 2024-01-03T10:31:47.950Z |
