Article No
GTX00598-09
Application | FC |
Article No | GTX00598-09 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
Clone | UCHT1 |
Clone Type | monoclonal |
Conjugation | PE/Cy5 |
Description | CD3 epsilon antibody [UCHT1] (PE-Cy5) |
Supplier | GeneTex |
Entrez Gene ID | 916 |
Gene Symbol | CD3E |
Immunogen | human thymocytes followed by Sezary T cells |
Isotype | IgG1 |
Notes | The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008] |
Product Type | Antibodies Primary |
Protocol | FACS: 4 µl reagent / 100 µl of whole blood or 10⁶ cells in a suspension. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications. |
Purification | Size-exclusion Chromatography |
Size | 100test |
Source / Host | mouse |
Species Reactivity | human, mammals |
Storage | 4°C |
UniProt Number | P07766 |
Product Page Updated | 2024-01-03T10:31:47.950Z |