Article No
D219-3
Anti-Desmoglein 3 (Mouse) mAb (No Azide)
Anti-Desmoglein 3 (Mouse) mAb (No Azide)
Antibodies Primary
Specifications
| Application | ICC, IHC, IP |
| Article No | D219-3 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | AK23 |
| Clone Type | monoclonal |
| Concentration | 1 mg/mL |
| Conjugation | Unconjugated |
| Description | Anti-Desmoglein 3 (Mouse) mAb (No Azide) |
| Supplier | MBL |
| Immunogen | Hybridoma of spleen cells and mouse myeloma cells P3 mouse model of PV |
| Isotype | IgG1 |
| Notes | Pemphigus vulgaris (PV) is a life -threatening autoimmune blistering disease of the skin and mucous membranes. In patients of PV, IgG autoantibodies against the cell surface of keratinocytes in stratified squamous epithelia play a major pathogenic role in loss of cell-cell adhesion. The autoimmune target of PV is desmoglein 3 (Dsg3), which is a member of the cadherin family of calcium-depending, transmembrane glycoprotein. |
| Product Type | Antibodies Primary |
| Research area | Immunology |
| Shipping Information | 4°C |
| Size | 100 µg |
| Source / Host | mouse |
| Species Reactivity | human, mouse |
| Stability | 1 year |
| Storage | 4°C |
| Substrate / Buffer | 100 μg IgG in 100 μl volume of PBS, pH 7.2. No preservative is contained. |
| Technical Specifications | Pemphigus vulgaris (PV) is a life -threatening autoimmune blistering disease of the skin and mucous membranes. In patients of PV, IgG autoantibodies against the cell surface of keratinocytes in stratified squamous epithelia play a major pathogenic role in loss of cell-cell adhesion. The autoimmune target of PV is desmoglein 3 (Dsg3), which is a member of the cadherin family of calcium-depending, transmembrane glycoprotein. |
| Product Page Updated | 2023-12-29T16:20:16.638Z |
