Article No
CSB-PA772050LD01DIL-50
Specifications
| Application | ELISA |
| Article No | CSB-PA772050LD01DIL-50 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone Type | polyclonal |
| Conjugation | Biotin |
| Description | vcp Antibody, Biotin conjugated |
| Supplier | Cusabio |
| Entrez Gene ID | 327197 |
| Gene Symbol | vcp |
| Immunogen | Recombinant Zebrafish Transitional endoplasmic reticulum ATPase protein (704-806AA) |
| Isotype | IgG |
| Notes | Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the nuclear envelope, and of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to the Golgi apparatus occurs via 50-70 nm transition vesicles which derive from part-rough, part-smooth transitional elements of the endoplasmic reticulum (tER). Vesicle budding from the tER is an ATP-dependent process. Also involved in DNA damage response: recruited to double-strand breaks (DSBs) sites and promotes the recruitment of tp53bp1 at DNA damage sites (By similarity). Enhances cell cycle progression and inhibits apoptosis at low temperatures (PubMed:12914916). Essential for the maturation of ubiquitin-containing autophagosomes and the clearance of ubiquitinated protein by autophagy (By similarity). Acts as a negative regulator of type I interferon production by promoting ubiquitination of ddx58/rig-i (By similarity). May play a role in the ubiquitin-dependent sorting of membrane proteins to lysosomes where they undergo degradation (By similarity). |
| Product Type | Antibodies Primary |
| Purification | Protein G Purified |
| Shipping Information | BLUE ICE |
| Size | 50ul |
| Source / Host | rabbit |
| Species Reactivity | zebrafish |
| Storage | -80°C |
| UniProt Number | Q7ZU99 |
| Product Page Updated | 2024-01-24T14:15:14.857Z |
