Article No
CSB-PA305523HC01EAH-50
Disintegrin EC3B
Disintegrin EC3B Antibody, FITC conjugated
Antibodies Primary
Specifications
| Application | ELISA, IF |
| Article No | CSB-PA305523HC01EAH-50 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone Type | polyclonal |
| Conjugation | FITC |
| Description | Disintegrin EC3B Antibody, FITC conjugated |
| Supplier | Cusabio |
| Immunogen | Recombinant Echis carinatus Disintegrin EC3B protein (1-67AA) |
| Isotype | IgG |
| Notes | Inhibits adhesion of cells expressing alpha-4/beta-1 (ITGA4/ITGB1) and alpha-4/beta-7 (ITGA4/ITGB7) integrins to the natural ligands vascular cell adhesion molecule 1 (VCAM-1) and mucosal addressin cell adhesion molecule 1 (MADCAM-1). It is also a weaker inhibitor of alpha-5/beta-1 (ITGA5/ITGB1) and alpha-2b/beta-3 (ITGA2B/ITGB3) integrins. The inhibitory activity of EC3 towards alpha-4 integrins is associated with the MLD sequence of EC3B subunit. The ability of EC3 to inhibit ITGA5/ITGB1 resides in both subunits A and B. |
| Product Type | Antibodies Primary |
| Purification | Protein G Purified |
| Shipping Information | BLUE ICE |
| Size | 50ug |
| Source / Host | rabbit |
| Species Reactivity | others |
| Storage | -80°C |
| UniProt Number | P81631 |
| Product Page Updated | 2024-01-24T13:11:22.259Z |
