Article No
CSB-PA199021-100
Application | ELISA, WB |
Article No | CSB-PA199021-100 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
Clone Type | polyclonal |
Conjugation | Unconjugated |
Description | ALKBH1 Antibody |
Supplier | Cusabio |
Entrez Gene ID | 8846 |
Gene Symbol | ALKBH1 |
Immunogen | Fusion protein of Human ALKBH1 |
Isotype | IgG |
Notes | This gene encodes a homolog to the E. coli alkB gene product. The E. coli alkB protein is part of the adaptive response mechanism of DNA alkylation damage repair. It is involved in damage reversal by oxidative demethylation of 1-methyladenine and 3-methylcytosine. Dioxygenase that repairs alkylated single-stranded DNA and RNA containing 3-methylcytosine by oxidative demethylation. Requires molecular oxygen, alpha-ketoglutarate and iron. May have a role in placental trophoblast lineage differentiation. Has DNA lyase activity and introduces double-stranded breaks at abasic sites. Cleaves both single-stranded DNA and double-stranded DNA at abasic sites, with the greatest activity towards double-stranded DNA with two abasic sites. |
Product Type | Antibodies Primary |
Purification | Affinity Purified |
Shipping Information | BLUE ICE |
Size | 100ul |
Source / Host | rabbit |
Species Reactivity | human, mouse |
Storage | -80°C |
UniProt Number | Q13686 |
Product Page Updated | 2024-01-24T13:11:22.259Z |