Article No
CSB-PA007791LB01HU-50
Specifications
| Application | ELISA |
| Article No | CSB-PA007791LB01HU-50 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone Type | polyclonal |
| Conjugation | HRP |
| Description | ERLIN2 Antibody, HRP conjugated |
| Supplier | Cusabio |
| Entrez Gene ID | 11160 |
| Gene Symbol | ERLIN2 |
| Immunogen | Recombinant Human Erlin-2 protein (25-206AA) |
| Isotype | IgG |
| Notes | Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs) such as ITPR1 (PubMed:19240031, PubMed:17502376). Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex (PubMed:21343306). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. May promote ER retention of the SCAP-SREBF complex (PubMed:24217618). |
| Product Type | Antibodies Primary |
| Purification | Protein G Purified |
| Shipping Information | BLUE ICE |
| Size | 50ug |
| Source / Host | rabbit |
| Species Reactivity | human |
| Storage | -80°C |
| UniProt Number | O94905 |
| Product Page Updated | 2024-01-24T13:11:22.259Z |
