Article No
CHI-HF-210CCL22-C050
Accession Number | AAH27952.1 |
Article No | CHI-HF-210CCL22-C050 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
Description | CCL22 (human):Fc (human) (rec.) |
Supplier | Adipogen Life Sciences |
Endotoxin | <0.06EU/µg protein (LAL test; Lonza). |
Format | Powder |
Notes | CCL22, also named stimulated T cell chemotactic protein (STCP1), is a CC chemokine initially isolated from clones of monocyte-derived macrophages and binds to the receptor CCR4. Human CCL22 is highly expressed in macrophage and in monocyte-derived dendritic cells and thymus. It is also found in lymph node, appendix, activated monocytes, resting and activated macrophages. May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. CCL22 has been shown to induce chemotaxis or Ca2+ mobilization in dendritic cells, IL-2 activated NK cells and activated T lymphocytes.|Protein. The extracellular domain of human CCL22 (aa 25-93) is fused to the N-terminus of the Fc region of human IgG1. Source: CHO cells. Endotoxin content: 98% (SDS-PAGE). CCL22, also named stimulated T cell chemotactic protein (STCP1), is a CC chemokine initially isolated from clones of monocyte-derived macrophages and binds to the receptor CCR4. Human CCL22 is highly expressed in macrophage and in monocyte-derived dendritic cells and thymus. It is also found in lymph node, appendix, activated monocytes, resting and activated macrophages. May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. CCL22 has been shown to induce chemotaxis or Ca2+ mobilization in dendritic cells, IL-2 activated NK cells and activated T lymphocytes. |
Alias Names | C-C Motif Chemokine 22; CC Chemokine STCP-1; Stimulated T Cell Chemotactic Protein 1; MDC; Macrophage-derived Chemokine; Small-inducible Cytokine A22 |
Product Type | Proteins & Peptides |
Purity | >98% |
Research Area | Immunology |
Sequence | The extracellular domain of human CCL22 (aa 25-93) is fused to the N-terminus of the Fc region of human IgG1. |
Shipping Information | BLUE ICE |
Size | 50 ug |
Source / Host | human |
Stability | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
Storage | -20°C, 4°C |
Substrate / Buffer | Lyophilized from 0.2µm-filtered solution in PBS. |
Technical Specifications | Protein. The extracellular domain of human CCL22 (aa 25-93) is fused to the N-terminus of the Fc region of human IgG1. Source: CHO cells. Endotoxin content: 98% (SDS-PAGE). CCL22, also named stimulated T cell chemotactic protein (STCP1), is a CC chemokine initially isolated from clones of monocyte-derived macrophages and binds to the receptor CCR4. Human CCL22 is highly expressed in macrophage and in monocyte-derived dendritic cells and thymus. It is also found in lymph node, appendix, activated monocytes, resting and activated macrophages. May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. CCL22 has been shown to induce chemotaxis or Ca2+ mobilization in dendritic cells, IL-2 activated NK cells and activated T lymphocytes. |
UniProt Number | AAH27952.1 |
Product Page Updated | 2024-02-01T08:25:01.492Z |