(-)-Cytisine

Article No CDX-C0228-M100
Product Type Chemicals & Biochemicals
Research Area Inflammation
Format Powder
Size 100 mg

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Specifications

CAS No 485-35-8
MW 190.2
Country Availability DK, EE, FI, IS, LT, LV, NO, SE
Data Sheet Link https://www.adipogen.com/productmanagement/resource/download/type/sheet/id/7594
Description (-)-Cytisine
Supplier Adipogen Life Sciences
Notes Chemical. CAS: 485-35-8. Formula: C11H14N2O. MW: 190.2. Synthetic. Pyridine-like alkaloid. Nicotine agonist. Potent agonist at alpha3beta4 and alpha7 nicotinic acetylcholine receptors and partial agonist at alpha4beta2 nicotinic acetylcholine receptors. Shows analgesic, antihypertensive and inotropic activities. Used for smoking cessation. Iron-chelator and hydroxyl radical scavanger. Has antidepressant properties. Used in forensics in novel surface molecular imprinting techniques.
Molecular Formula C11H14N2O
Alias Names NSC 407282; BRN 0083882; Baptitoxine; Sophorine; (1S,5R)-3,4,5,6-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-8(2H)-one
Purity >99% (CHN)
References (1) R.L. Papke & S.F. Heinemann; Mol. Pharmacol. 45, 142 (1994) | (2) B.W. Wenger, et al.; J. Pharmacol. Exp. Ther. 281, 905 (1997) | (3) B. Ferger, et al.; Eur. J. Pharmacol. 360, 155 (1998) | (4) Y.E. Slater, et al.; Neuropharmacology 44, 503 (2003) | (5) P. Tutka & W. Zatonski; Pharmacol. Rep. 58, 777 (2006) (Review) | (6) J.F. Etter, et al.; Drug Alcohol Depend. 92, 3 (2008) (Review) | (7) Y.F. Li, et al.; Auton. Neurosci. 154, 14 (2010) | (8) E.G. Perez, et al.; Nat. Prod. Rep. 29, 555 (2012) (Review)
Solubility Soluble in toluene.
Storage -20°C
Technical Specifications Pyridine-like alkaloid. Nicotine agonist. Potent agonist at alpha3beta4 and alpha7 nicotinic acetylcholine receptors and partial agonist at alpha4beta2 nicotinic acetylcholine receptors. Shows analgesic, antihypertensive and inotropic activities. Used for smoking cessation. Iron-chelator and hydroxyl radical scavanger. Has antidepressant properties. Used in forensics in novel surface molecular imprinting techniques.

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