Article No
CDX-C0042-G001
CAS No | 127770-45-0 |
MW | 529.28 |
Article No | CDX-C0042-G001 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
Description | Carboxy-DCFDA |
Supplier | Adipogen Life Sciences |
Format | Powder |
Notes | Chemical. CAS: 127770-45-0. Formula: C25H14Cl2O9. MW: 529.28. Synthetic. Intracellular esterase substrate with low sensitivity of fluorescence to intracellar pH.|Non-activated, amine-reactive fluorescent probe. Mixture of 5/6-isomers of CDCFDA that can be used in biomolecules conjugation. 5(6)-CDCFDA is an amine-reactive fluorescein diacetate (FDA) derivative used to prepare a variety of FDA conjugates. 5(6)-CDCFDA is a non-fluorescent molecule that diffuse into cells and is hydrolyzed by intracellular non-specific esterases, yielding a fluorescent probe. The probe accumulates exclusively in viable cells with intact cell membranes. 5(6)-CDCFDA does not stain dead cells. 5(6)-CDCFDA labeling can be used for monitoring cells by flow cytometry or fluorescence microscopy. The probe is also frequently used to monitor reactive oxygen species (ROS) generation in live cells and intracellular pH levels. Spectral data: lambdaex=504nm, lambdaem=529nm. |
Molecular Formula | C25H14Cl2O9 |
Alias Names | 5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate |
Product Type | Chemicals & Biochemicals |
Purity | >85% |
Research Area | Immunology |
Shipping Information | RT |
Size | 1 g |
Solubility | Soluble in DMSO, DMF or methanol. |
Stability | Stable for at least 2 years after receipt when stored at +4°C. |
Storage | 4°C |
Technical Specifications | Chemical. CAS: 127770-45-0. Formula: C25H14Cl2O9. MW: 529.28. Synthetic. Intracellular esterase substrate with low sensitivity of fluorescence to intracellar pH. |
Product Page Updated | 2024-02-01T08:25:01.492Z |