3,28-Di-O-(3,3-dimethylglutaryl)betulin

Article No BVT-0404-M001
Product Type Chemicals & Biochemicals
Research Area Inflammation
Format Powder
Size 1 mg

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Specifications

CAS No n.d.
MW 727
Country Availability DK, EE, FI, IS, LT, LV, NO, SE
Data Sheet Link https://www.adipogen.com/productmanagement/resource/download/type/sheet/id/8284
Description 3,28-Di-O-(3,3-dimethylglutaryl)betulin
Supplier Adipogen Life Sciences
Notes Chemical. Formula: C44H70O8. MW: 727. Semi-synthetic derivative from betulin (from birch bark). Semi-synthetic derivative of betulin (from birch bark). Potent antiviral compound. Shows anti-HIV activity (more active than AZT in vitro).
Molecular Formula C44H70O8
Alias Names 3,28-di(diMeG)betulin; NSC705961; Betulin 3,28-(3,3-dimethyl)glutarate
Purity >97% (HPLC)
References Anti-AIDS agents. 32. Synthesis and anti-HIV activity of betulin derivatives: I.-C. Sun, et al.; Bioorg. Med. Chem. Lett. 8, 1267 (1998) | Anti-AIDS agents. 34. Synthesis and structure-activity relationships of betulin derivatives as anti-HIV agents: I.-C. Sun, et al.; J. Med. Chem. 41, 4648 (1998) | 3,28-Di-O-(dimethylsuccinyl)-betulin isomers as anti-HIV agents: Y. Kashiwada, et al.; Bioorg. Med. Chem. Lett. 11, 183 (2001) | 3-O-Glutaryl-dihydrobetulin and related monoacyl derivatives as potent anti-HIV agents: Y. Kashiwada, et al.; Bioorg. Med. Chem. Lett. 14, 5851 (2004) | Birch bark research and development: P.A. Krasutsky; Nat. Prod. Rep. 23, 919 (2006) | Pharmacological properties of the ubiquitous natural product betulin: S. Alakurtti, et al.; Eur. Pharm. Sci. 29, 1 (2006)
Solubility Soluble in methanol, acetone or DMSO.
Storage -20°C
Technical Specifications Semi-synthetic derivative of betulin (from birch bark). Potent antiviral compound. Shows anti-HIV activity (more active than AZT in vitro).

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