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|Country Availability||DK, EE, FI, IS, LT, LV, NO, SE|
|Data Sheet Link||https://www.adipogen.com/productmanagement/resource/download/type/sheet/id/8488|
|Supplier||Adipogen Life Sciences|
|Notes||Modified base of mammalian DNA. Involved in regulation of stem cell processes, cellular development, neurodegeneration and carcinogenesis. Important epigenetic marker. Related to bacimethrin (Prod. No. BVT-0226 http://www.adipogen.com/bvt-0226/bacimethrin.html ).|
|Alias Names||5hmC; Demethylbacimethrin|
|References||5-Hydroxymethylcytosine, the sixth base of the genome: M. Münzel, et al.; Angew. Chem. Int. Ed. 50, 6420 (2011) (Review) | 5-Hydroxymethylcytosine-mediated DNA demethylation in stem cells and development: W. Sun; Stem Cells 23, 923 (2014) (Review) | 5-Hydroxymethylcytosine: an epigenetic mark frequently deregulated in cancer: L. Kroetze, et al.; Biochim. Biophys. Acta 144, 1855 (2015) (Review) | 5-Hydroxymethylcytosine: a new player in brain disorders?: Y. Cheng, et al.; Exp. Neurol. 268, 3 (2015) (Review) | 5-Hydroxymethylcytosine: in cancer: significance in diagnosis and therapy: A. Vasanthakumar & L. A. Godley; Cancer Genet. 208, 167 (2015) (Review) | New themes in the biological functions of 5-methylcytosine and 5-hydroxymethylcytosine: E. Moen, et al.; Immunol. Rev. 236, 36 (2015) (Review) | Role of 5-hydroxymethylcytosine in neurodegeneration: S. I. Sherwani & H. A. Khan; Gene 570, 17 (2015) (Review)|
|Solubility||Soluble in water, DMSO or methanol.|
|Technical Specifications||Chemical. CAS: 1123-95-1. Formula: C5H7N3O2. MW: 141.1. Synthetic. Modified base of mammalian DNA. Involved in regulation of stem cell processes, cellular development, neurodegeneration and carcinogenesis. Important epigenetic marker. Related to bacimethrin (Prod. No. BVT-0226 http://www.adipogen.com/bvt-0226/bacimethrin.html ).|
|Product Page Updated||2019-01-09T14:34:57.552Z|
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