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N-Methyl-1-deoxynojirimycin

Chemicals & Biochemicals

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Article No

BVT-0130-M001

Size

1 mg

Shipping Information

Article No

BVT-0130-M001

Size

1 mg

Specifications

CAS No	69567-10-8
MW	177.2
Article No	BVT-0130-M001
Country Availability	SE, FI, DK, NO, IS, EE, LV, LT
Description	N-Methyl-1-deoxynojirimycin
Supplier	Adipogen Life Sciences
Format	Powder
Notes	alpha-Glucosidase inhibitor. Glucosidase I inhibitor (IC50=0.3µM), 10-fold more potent over 1-Deoxynojirimycin (dNM). Inhibitor of glycoprotein processing. Strong glycosyltransferase (GTF) inhibitor. Angiogenesis inhibitor. Reduces the size of myocardial infarcts.\|Chemical. CAS: 69567-10-8. Formula: C7H15NO4. MW: 177.2. Isolated from Streptomyces sp. alpha-Glucosidase inhibitor. Inhibitor of glycoprotein processing. Strong glycosyltransferase (GTF) inhibitor. Angiogenesis inhibitor. Reduces the size of myocardial infarcts.
Molecular Formula	C7H15NO4
Alias Names	N-Methylmoranoline; MOR-14; 1,5-Dideoxy-1,5-(methylimino)-D-glucitol
Product Type	Chemicals & Biochemicals
Purity	>98%
Research area	Metabolism
Shipping Information	RT
Size	1 mg
Solubility	Soluble in DMSO or water.
Stability	Stable for at least 1 year after receipt when stored at +4°C.
Storage	-20°C, 4°C
Technical Specifications	Chemical. CAS: 69567-10-8. Formula: C7H15NO4. MW: 177.2. Isolated from Streptomyces sp. alpha-Glucosidase inhibitor. Inhibitor of glycoprotein processing. Strong glycosyltransferase (GTF) inhibitor. Angiogenesis inhibitor. Reduces the size of myocardial infarcts.
Product Page Updated	2024-02-01T08:25:01.492Z

Documentation

Datasheet

MSDS

References

N-methyl-1-deoxynojirimycin, a novel inhibitor of glycoprotein processing, and its effect on fowl plague virus maturation: P.A. Romero, et al.; Virology 130, 238 (1983) | Effect of N-methyl-1-deoxy-nojirimycin on the degradation of cellobiose by Cellulomonas cartalyticum: H. Sahm, et al.; Appl. Microbiol. Biotechnol. 20, 54 (1984) | Comparison between 1-deoxynojirimycin and N-methyl-1-deoxynojirimycin as inhibitors of oligosaccharide processing in intestinal epithelial cells: P.A. Romero, et al.; Biochem. J. 226, 733 (1985) | Different effects of glucosidase inhibitors 1-deoxynojirimycin, N-methyl-1-deoxynojirimycin and castanospermine on the glycosylation of rat alpha1-proteinase inhibitor and alpha1-acid glycoprotein: V. Gross, et al.; Biochem. J. 236, 853 (1986) | Inhibition of myoblast fusion by the glucosidase inhibitor N-methyl-1-deoxynojirimycin, but not by the mannosidase inhibitor 1-deoxymannojirimycin: P.C. Holland, et al.; Biochem. J. 238, 335 (1986) | The glycoprotein-processing inhibitors bromoconduritol and N-methyl-1-deoxynojirimycin alter the adhesion phenotype of skeletal myoblasts: G.C. Trudel, et al.; Biochem. Cell Biol. 68, 1411 (1990) | Subsite specificity of the active site of glucosyltransferases from Streptococcus sobrinus: K.S. Devulapalle & G. Mooser; J. Biol. Chem. 269, 11967 (1994) | N-methyl-1-deoxynojirimycin (MOR-14), an alpha-glucosidase inhibitor, markedly reduced infarct size in rabbit hearts: M. Arai, et al.; Circ. Res. 97, 1290 (1998) | N-methyl-1-deoxynojirimycin (MOR-14), an alpha-glucosidase inhibitor, markedly improves postischemic left ventricular dysfunction: Y. Nishida, et al.; Heart Vessels 15, 268 (2000) | Combination of N-methyl-1-deoxynojirimycin and ischemic preconditioning markedly reduces the size of myocardial infarcts in rabbits: D.-J. Wu, et al.; Circ. J. 65, 673 (2001) | Role of protein kinase C in the reduction of infarct size by N-methyl-1-deoxynojirimycin, an alpha-1,6-glucosidase inhibitor: M. Arai, et al.; Br. J. Pharmacol. 135, 635 (2001) | Biological study of the angiogenesis inhibitor N-(8-(3-ethynylphenoxy)octyl-1-deoxynojirimycin: Y. Zhao, et al.; Chem. Biol. Drug Des. 75, 570 (2010)

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