Article No
BT-EGCRY2-1
Specifications
| MW | ~36kDa |
| Article No | BT-EGCRY2-1 |
| Biosite Brand | Biosite |
| Country Availability | all |
| Description | CD109 |
| Supplier | Nordic Biosite |
| Notes | CD109 is a glycosylphosphatidylinositol (GPI)-linked glycoprotein that belongs to the alpha2-macroglobulin family of thioester containing proteins. CD109 is associated with TGF-beta receptor I (TbRI) and inhibits TGF-beta signaling. Cleavage of CD109 at its Furin cleavage site results in the release of its large amino-terminal domain, which then binds to the TGF-beta receptor I to inhibit TGF-beta signaling. CD109 is expressed on a subset of CD34+ bone marrow cells and mesenchymal stem cells, activated platelets, activated T cells, endothelial cells, and a wide variety of tumors. Elevated CD109 expression has been considered a diagnostic/prognostic marker for several types of cancers. |
| Product Type | Proteins & Peptides |
| Purification | Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE). |
| Purity | Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE). |
| Sequence | CTGAGCAGTGTGGGCAGCCCGAAAGCAAAAGAAGCACTGAATATGCTGACCTGGCGCGCAGAACAGGAAGGTGGCATGCAGTTCTGGGTGAGCAGTGAAAGCAAACTGAGCGATAGTTGGCAGCCGCGTAGCCTGGATATTGAAGTTGCAGCCTATGCACTGCTGAGTCACTTCCTGCAGTTCCAGACCAGCGAAGGTATTCCGATTATGCGTTGGCTGAGCCGTCAGCGCAATAGTCTGGGCGGCTTCGCAAGTACCCAGGATACCACCGTGGCCCTGAAAGCCCTGAGCGAATTCGCAGCACTGATGAATACCGAACGCACCAATATTCAGGTTACCGTGACCGGCCCGAGTAGCCCGAGCCCTGTGAAATTCCTGATTGATACCCATAATCGTCTGCTGCTGCAGACCGCAGAACTGGCAGTTGTGCAGCCGACCGCCGTTAATATTAGTGCCAATGGCTTCGGCTTCGCAATCTGTCAGCTGAATGTGGTGTATAATGTGAAAGCCAGTGGTAGCAGCCGCCGCCGCCGCAGCATTCAGAATCAGGAAGCATTCGATCTGGATGTGGCCGTTAAAGAAAATAAAGATGATCTGAATCACGTGGATCTGAATGTGTGTACCAGCTTCAGTGGCCCGGGTCGCAGTGGCATGGCACTGATGGAAGTTAATCTGCTGAGCGGCTTCATGGTTCCGAGTGAAGCAATTAGTCTGAGCGAAACCGTGAAAAAAGTTGAATATGATCATGGTAAGCTGAATCTGTATCTGGATAGTGTTAATGAAACACAATTCTGTGTGAATATCCCGGCAGTGCGTAACTTCAAAGTTAGCAATACCCAGGATGCAAGCGTTAGCATTGTGGATTATTATGAACCGCGCCGTCAGGCCGTGCGTAGCTATAATAGCGAAGTGAAACTGAGTAGTTGTGATCTGTGCAGTGATGTGCAGGGTTGTCGTCCGTGCGAAGATGGTGCA |
| Size | 1mg |
| Source / Host | bacteria |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
| Substrate / Buffer | PBS, 4M Urea, PH7.4 |
| Swiss-Prot No | Q6YHK3 |
| Product Page Updated | 2024-01-04T12:20:49.260Z |