DMRTC2

Article No BT-46F22B
Application WB
Size 100ul

Specifications

MW ~ 39 kDa
Additional Information For research use only, not for use in diagnostic procedure.
Country Availability all
BioSite Brand BioSite
Description DMRTC2 polyclonal antibody
Supplier BioSite
Immunogen A synthetic peptide corresponding to residues in Human DMRTC2
Notes In humans, the DMRT (doublesex and mab-3 related transcription factor) genes encode a large family of transcription factors that are related to the Drosophila doublesex proteins. Expressed primarily in the gonads, DMRT proteins contain cysteine-rich DNA-binding motifs and are thought to play an important role in sexual development. DMRTC2 (DMRT-like family C2) is a 367 amino acid nuclear protein that exists as two alternatively spliced isoforms and belongs to the DMRT family. Involved in sexual development, DMRTC2 is expressed in pancreas and testis and contains one DM DNA-binding domain. The gene encoding DMRTC2 maps to human chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs).
Alias Names Doublesex- and mab-3-related transcription factor C2; DMRTC2
Protocol WB: 1:500~1:1000
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Size 100
Source / Host rabbit
Species Reactivity human, mouse
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Substrate / Buffer 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Swiss-Prot No Q8IXT2
Product Page Updated 2018-10-30T14:48:19.515Z

Shipping info

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Source/Host:

rabbit rabbit

Species reactivity:

human, mouse human mouse

Suggested protocols:

Western Blot

Western Blot