Pan Cytokeratin

Pan Cytokeratin

Article No BSH-7124-100
Product Type Antibodies Primary
Application IHC-P
Format Optibodies, Concentrate
Size 0,1 ml

Specifications

Alias Names Optibodies, CK, Keratin, pan CK, Optibody
Clone BS5
Conjugation Unconjugated
Description Anti-human Pan Cytokeratin mouse monoclonal, CE certified (IVD)
Immunogen aa 316-589
Notes Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation which is directly applicable to the characterization of malignant tumors.
Source / Host mouse
Species Reactivity human, dog/canine
Storage
Substrate / Buffer TRIS with 0.03% sodium azide, pH7,2
Supplier Nordic BioSite

Shipping info

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CE certified

Species reactivity:

human, dog/canine