Article No
BSH-7082-1
Desmin
Anti-Desmin, mouse monoclonal - Optibodies
Antibodies Primary
Specifications
| Application | IHC |
| Article No | BSH-7082-1 |
| Biosite Brand | Optibodies |
| Country Availability | all |
| Clone | BS21 |
| Clone Type | monoclonal |
| Control Tissue | Appendix, Placenta, leiomyoma |
| Description | Anti-Desmin, mouse monoclonal - Optibodies |
| Recommended Dilution | IHC-P (1:100 - 1:400) |
| Supplier | Nordic Biosite |
| Format | Concentrate |
| Notes | Desmin (DES), with 470-amino acid protein (about 52kDa), belongs to the intermediate filament family and Desmin is class III intermediate filaments found in muscle cells. Homopolymers of Desmin form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane.Mutations in Desmin are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.Desmin is also expressed in smooth muscle cells of both airways and alveolar ducts and Desmin is a load-bearing protein that stiffens the airways and consequently the lung and modulates airway contractile response. |
| Alias Names | Desmin, DES |
| Product Type | Antibodies Primary |
| Protocol | suitable for IHC-P,IHC-Fr |
| Size | 1 ml |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | Store at 4℃ |
| Substrate / Buffer | TRIS with 0.03% sodium azide, pH7,2 |
| Technical Specifications | Control: Appendix, Placenta, leiomyoma |
| UniProt Number | P17661 |
| Product Page Updated | 2023-03-24T19:16:54.901Z |