Antibodies Primary

Desmin

NEW
Anti-Desmin, mouse monoclonal - Optibodies

Article No

BSH-7082-1

Application

IHC

Species Reactivity

human

Size

1 ml

Clone

BS21

Source / Host

mouse

Specifications

Application IHC
Article No BSH-7082-1
BioSite Brand Optibodies
Country Availability all
Clone BS21
Clone Type monoclonal
Control Tissue Appendix, Placenta, leiomyoma
Description Anti-Desmin, mouse monoclonal - Optibodies
Recommended Dilution IHC-P (1:100 - 1:400)
Supplier Nordic BioSite
Format Concentrate
Notes Desmin (DES), with 470-amino acid protein (about 52kDa), belongs to the intermediate filament family and Desmin is class III intermediate filaments found in muscle cells. Homopolymers of Desmin form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane.Mutations in Desmin are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.Desmin is also expressed in smooth muscle cells of both airways and alveolar ducts and Desmin is a load-bearing protein that stiffens the airways and consequently the lung and modulates airway contractile response.
Alias Names Desmin, DES
Product Type Antibodies Primary
Protocol suitable for IHC-P,IHC-Fr
Size 1 ml
Source / Host mouse
Species Reactivity human
Storage Store at 4℃
Substrate / Buffer TRIS with 0.03% sodium azide, pH7,2
Technical Specifications Control: Appendix, Placenta, leiomyoma
UniProt Number P17661
Product Page Updated 2021-08-03T14:21:48.888Z

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