Article No
BPS-81081
AMSH Core Domain, His-tag Recombinant
AMSH Core Domain, His-tag Recombinant
Proteins & Peptides
Specifications
| MW | 20.5 kDa |
| Additional Information | AMSHcore (Associated Molecule with the SH3-domain of STAM) is a JAMM domain-containing protein that regulates receptor endosomal sorting of the epidermal growth factor receptor (EGFR). Recombinant AMSH functions as a deubiquitylase in vitro and ablation of AMSH activity by incubation of cells with AMSH siRNA enhances the degradation of EGFR. AMSHcore mediated cleavage of K63 linked ubiquitin chains is enhanced in the presence of its binding partner STAM. AMSHcore contains only the core domain of AMSH protein. |
| Article No | BPS-81081 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Description | AMSH Core Domain, His-tag Recombinant |
| Supplier | BPS Bioscience |
| Entrez Gene ID | 57559 |
| Format | Aqueous buffer solution |
| Gene Symbol | STAMBPL1 |
| Notes | Human AMSH Core Domain recombinant protein, a.a. 250-424, with His-tag, expressed in E. coli. |
| Alias Names | Associated molecule with the SH3 domain of STAM, STAMBP, MGC126516, MGC126518, STAM-binding protein |
| Product Type | Proteins & Peptides |
| Shipping Information | -80°C (dry ice) |
| Size | 25 µg |
| Species Reactivity | human |
| Storage | Store at or below -80°C. Stable as supplied for up to 1 year when stored dessicated at -80°C. |
| Technical Specifications | This enzyme cleaves K63-linked ubiquitin chains in vitro. Suggested Substrate: DiUbiquitin K63 |
| UniProt Number | Q96FJ0 |
| Product Page Updated | 2024-01-09T13:23:45.900Z |
