Article No
BPS-60535
PD-1 / NFAT Reporter - Jurkat Recombinant Cell Line
PD-1 / NFAT Reporter - Jurkat Recombinant Cell Line
Cells
Specifications
| Accession Number | NM_005018 |
| Additional Information | The binding of Programmed Cell Death Protein 1 (PD-1), a receptor expressed on activated Tcells, to its ligands, PD-L1 and PD-L2, negatively regulates immune responses. The PD-1 ligands are found on most cancers, and PD-1:PD-L1/2 interaction inhibits T cell activity and allows cancer cells to escape immune surveillance. The PD-1:PD-L1/2 pathway is also involved in regulating autoimmune responses, making these proteins promising therapeutic targets for a number of cancers, as well as multiple sclerosis, arthritis, lupus, and type I diabetes. |
| Article No | BPS-60535 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Components | Each vial contains 2 X 106 cells in 1 ml of 10% DMSO |
| Description | PD-1 / NFAT Reporter - Jurkat Recombinant Cell Line |
| Supplier | BPS Bioscience |
| Format | Aqueous solution containing DMSO |
| Notes | Recombinant Jurkat T cell expressing firefly luciferase gene under the control of NFAT response elements with constitutive expression of human PD-1 (Programmed Cell Death 1, PDCD1, SLEB2, CD279, GenBank Accession #NM_005018). |
| Alias Names | Programmed cell death 1, PDCD1, PD-1, PD1, SLEB2, CD279, HPD-L, PD1/NFAT, PD-1 NFAT, PD-1/NFAT |
| Product Type | Cells |
| Shipping Information | -80°C (dry ice) |
| Size | 2 vials |
| Source / Host | human |
| Storage | Immediately upon receipt, store in liquid nitrogen. |
| Technical Specifications | • Screen for activators or inhibitors of PD-1 signaling in a cellular context • Characterize the biological activity of PD-1 and its interactions with ligands |
| Product Page Updated | 2024-01-09T13:23:45.900Z |
