Article No
BPS-40402
BMX, GST-tag Recombinant
BMX, GST-tag Recombinant
Proteins & Peptides
Specifications
| MW | 110 kDa |
| Accession Number | NM_001721 |
| Additional Information | The BMX gene encodes a non-receptor tyrosine kinase, which may play a role in the growth and differentiation of hematopoietic cells (1). The BMX gene is located on chromosomal band Xp22.2 between the DXS197 and DXS207 loci. Interestingly, chromosome X also contains the closest relative of BMX, the BTK gene, implicated in X-linked agammaglobulinemia. BMX, is found to induce activation of the Stat signaling pathway (2). |
| Article No | BPS-40402 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Description | BMX, GST-tag Recombinant |
| Supplier | BPS Bioscience |
| Entrez Gene ID | 660 |
| Format | Aqueous buffer solution |
| Gene Symbol | BMX |
| Notes | Recombinant full-length human cytoplasmic tyrosine-protein kinase BMX (BMX), also known as bone marrow tyrosine kinase gene in chromosome X protein, epithelial and endothelial tyrosine kinase, ETK, and NTK38 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag, a.a. 1-675 (end). The gene accession number is NM_001721 (variant 2). |
| Alias Names | ETK, PSCTK2, PSCTK3, bone marrow tyrosine kinase gene in chromosome X protein, epithelial and endothelial tyrosine kinase, NTK38 |
| Product Type | Proteins & Peptides |
| Protocol | Assay was done in_x000D_ Kinase buffer containing 0.2 mM DTT_x000D_ using Poly-(Tyr,Glu) substrate (0.2_x000D_ mg/ml) and 20 mM ATP. Reaction was_x000D_ done at 30°C for 45 min. Amount of ATP_x000D_ transferred was measured using Kinase-_x000D_Glo reagent (Promega) |
| Shipping Information | -80°C (dry ice) |
| Size | 10 µg |
| Source / Host | insect |
| Species Reactivity | human |
| Storage | At least 6 months at -80°C. |
| Substrate / Buffer | 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol |
| Technical Specifications | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
| UniProt Number | P51813 |
| Product Page Updated | 2024-01-09T13:23:45.900Z |
