Article No
BPS-40026
AMPK (A2/B2/G1), His-tags Recombinant
AMPK (A2/B2/G1), His-tags Recombinant
Proteins & Peptides
Specifications
| MW | ~146 kDa (complex) |
| Accession Number | NM_002733, NM_005399, NM_006252 |
| Additional Information | AMP-activated protein kinase (AMPK) exhibits a key role as a master regulator of cellular energy homeostasis (1). AMPK exists as a heterotrimeric complex composed of a catalytic α subunit and regulatory β and γ subunits. Binding of AMP to the γ subunit allosterically activates the complex. AMPK is activated in response to stresses that deplete cellular ATP (low glucose, hypoxia and ischemia) and via signaling pathways in response to adiponectin, leptin and CAMKKβ (2). |
| Article No | BPS-40026 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Description | AMPK (A2/B2/G1), His-tags Recombinant |
| Supplier | BPS Bioscience |
| Format | Aqueous buffer solution |
| Notes | Recombinant human AMPK (combination of A2/B2/G1 subunits), full length, with C-terminal His-tags, expressed in Sf9 insect cells via a baculovirus expression system. MW = 69 kDa (A2), 36 kDa (B2), 41 kDa (G1). |
| Alias Names | Subunit A2: PRKAA2, AMPK, AMPK2, PRKAA Subunit B2: PRKAB2, MGC61468 Subunit G1: PRKAG1, AMPKG, MGC8666 |
| Product Type | Proteins & Peptides |
| Purity | ≥75% |
| Shipping Information | -80°C (dry ice) |
| Size | 10 µg |
| Source / Host | insect |
| Species Reactivity | human |
| Storage | At least 6 months at -80°C. |
| Substrate / Buffer | 50 mM sodium phosphate, pH 7.0, 300 mM NaCl, 150 mM imidazole, 0.1 mM PMSF, 0.25 mM DTT, 25% glycerol. |
| Technical Specifications | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
| UniProt Number | A2: P54646; B2: O43741; G1: P54619 |
| Product Page Updated | 2024-01-09T13:23:45.900Z |
