Article No
BPS-40022
AMPK (A1/B1/G3), His-tags Recombinant
AMPK (A1/B1/G3), His-tags Recombinant
Proteins & Peptides
Specifications
| MW | ~157 kDa (complex) |
| Accession Number | NM_006251, NM_006253, NM_017431 |
| Additional Information | AMPK (A1/B1/G3) is a member of the AMPK family which are heterotrimeric proteins consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPKs are an important energy-sensing enzyme group in the cells that monitor energy status particularly in response to stress (1). AMPKs regulate fatty acid and cholesterol synthesis by regulating the key rate-limiting enzymes acetyl-CoA carboxylase and hydroxy beta-methylglutaryl-CoA reductase. The γ subunit is dominantly expressed in skeletal muscle where it may play a key role in the regulation of energy metabolism (2). |
| Article No | BPS-40022 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Description | AMPK (A1/B1/G3), His-tags Recombinant |
| Supplier | BPS Bioscience |
| Format | Aqueous buffer solution |
| Notes | Recombinant human AMPK (combination of A1/B1/G3 subunits), full length, with C-terminal His-tags, expressed in Sf9 insect cells via a baculovirus expression system. MW = 68 kDa (A1), 38 kDa (B1), 51 kDa (G3). |
| Alias Names | Subunit A1: PRKAA1, MGC33776, MGC57364 Subunit B1: PRKAB1, AMPK, HAMPKb, MGC17785 Subunit G3: PRKAG3 |
| Product Type | Proteins & Peptides |
| Purity | ≥75% |
| Shipping Information | -80°C (dry ice) |
| Size | 10 µg |
| Source / Host | insect |
| Species Reactivity | human |
| Storage | At least 6 months at -80°C. |
| Substrate / Buffer | 50 mM sodium phosphate, pH 7.0, 300 mM NaCl, 150 mM imidazole, 0.1 mM PMSF, 0.25 mM DTT, 25% glycerol. |
| Technical Specifications | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
| UniProt Number | A1: Q13131; B1: Q9Y478; G3: Q9UGI9 |
| Product Page Updated | 2024-01-09T13:23:45.900Z |
