Article No
BPS-101246
Spike Neutralizing Antibody (Clone LxC1-G10) (SARS-CoV-2)
Spike Neutralizing Antibody (Clone LxC1-G10) (SARS-CoV-2)
Antibodies Primary
Specifications
| MW | 150 kDa |
| Additional Information | This human monoclonal antibody recognizes SARS-CoV-2 full-length spike proteins in the native trimeric conformation. This antibody cross-reacts with the wildtype (BPS Bioscience #100728) as well as the Alpha B.1.1.7 (BPS Bioscience #510334), Beta B.1.351 (BPS Bioscience #510333), Beta B.1.351Δ242-244 (BPS Bioscience #101091), Gamma P.1 (BPS Bioscience #100989), Delta B.1.617.2 (BPS Bioscience #101147) and Delta Plus B.1.617.2.1 (BPS Bioscience #101165) variant spike trimers [Table of variants]. The human ACE2 receptor is found on the surface of type I and II pneumocytes, endothelial cells, and ciliated bronchial epithelial cells. ACE2 is known to mediate COVID-19 infection through direct binding of the SARS-CoV-2 Spike protein. This neutralizing antibody has been functionally tested using BPS Bioscience Spike Trimer: ACE2 Inhibitor Screening Kits (available for purchase). |
| Article No | BPS-101246 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | Clone LxC1-G10) |
| Clone Type | monoclonal |
| Description | Spike Neutralizing Antibody (Clone LxC1-G10) (SARS-CoV-2) |
| Supplier | BPS Bioscience |
| Format | Aqueous buffer solution. |
| Isotype | IgG1 |
| Notes | This human monoclonal antibody recognizes SARS-CoV-2 full-length spike proteins in the native trimeric conformation. This antibody cross-reacts with the wildtype (BPS Bioscience #100728) as well as the Alpha B.1.1.7 (BPS Bioscience #510334), Beta B.1.351 (BPS Bioscience #510333), Beta B.1.351Δ242-244 (BPS Bioscience #101091), Gamma P.1 (BPS Bioscience #100989), Delta B.1.617.2 (BPS Bioscience #101147) and Delta Plus B.1.617.2.1 (BPS Bioscience #101165) variant spike trimers [Table of variants]. The human ACE2 receptor is found on the surface of type I and II pneumocytes, endothelial cells, and ciliated bronchial epithelial cells. ACE2 is known to mediate COVID-19 infection through direct binding of the SARS-CoV-2 Spike protein. This neutralizing antibody has been functionally tested using BPS Bioscience Spike Trimer: ACE2 Inhibitor Screening Kits (available for purchase). |
| Alias Names | covid, covid-19, covid19, coronavirus, B1135 antibody, Brazil antibody, B117 antibody, SARS neutralizing antibody, trimer neutralizing antibody, UK variant antibody, SARS CoV 2 neutralizing antibody, South African variant Antibody |
| Product Type | Antibodies Primary |
| Purification | Protein A |
| Shipping Information | -20°C or -80°C |
| Size | 100 µg |
| Storage | -20°C. Stable for at least 6 months from date of receipt. |
| Substrate / Buffer | 1X PBS, 0.2% BSA |
| Product Page Updated | 2024-01-09T13:23:45.900Z |
