CD16/CD32
Specifications
| Country Availability | SE, FI, DK, NO, EE, LV, LT |
| Clone | 2.4G2 |
| Description | InVivoMAb anti-mouse CD16/CD32 |
| Supplier | BioXcell |
| Immunogen | BALB/c mouse macrophage cell line J774 |
| Isotype | IgG2b, k |
| Notes | The 2.4G2 monoclonal antibody reacts specifically with mouse CD16 (FcγRIII) and CD32 (FcγRII). It has also been reported to react non-specifically via its Fc domain to FcγRI. CD16 and CD32 are expressed on B cells, monocytes/macrophages, NK cells, granulocytes, mast cells, and dendritic cells. These receptors bind to the Fc portion of antibody-antigen complexes and play a role in adaptive immune responses. The 2.4G2 antibody is commonly used in flow cytometry staining experiments to prevent non-specific binding of IgG to the FcγIII and FcγII, and possibly FcγI, receptors prior to staining with antigen specific primary antibodies. The Fab fragments of the 2.4G2 antibody have also been used to block Fc receptors in vivo. |
| Purity | >95%. Determined by SDS-PAGE |
| Source / Host | rat |
| Storage | Undiluted at 4°C in the dark |
| Substrate / Buffer | PBS, pH 8.0. Contains no stabilizers or preservatives |
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Shipping info
The delivery time for this item is approximately 5-8 business days. If other deviations occur, this will be noted on the order confirmation or communicated via email. Please note, we do reserve the right to select the best packaging and shipping method in order to insure the stability of the product and allow efficient order tracking.
Source/Host:
rat
