Article No
Ab00803-10.3
Accession Number | P10845 |
Additional Information | This is a recombinant monoclonal antibody. |
Application | Neutralization, FC |
Article No | Ab00803-10.3 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
Clone | CR1 |
Clone Type | recombinant |
Conjugation | Unconjugated |
Description | Anti-Botulinum neurotoxin type A [CR1] |
Supplier | Absolute Antibody |
Format | Purified |
Isotype | IgG1 |
Notes | CR1 was produced by a yeast gene diversity library used to increase the affinitiy of scFv AR2 for BoNT/A2, while maintinaing high affinity binding to BoNT/A2. AR2 was generated after multiple rounds of affinity maturation of the humanized C25, which itself was created by CDR-grafting from the parental murine C25. Murine C25 was prepared by constructing a scFv phage display library from mice immunized with recombinant BoNT/A binding domain (Hc). |
Alias Names | BoNT/A; BoNT; Botulinum neurotoxin; Bontoxilysin-A; Bontoxilysin A; BOTOX |
Product Type | Antibodies Primary |
Purification | Purified |
Research area | Neuroscience |
Shipping Information | Wet Ice |
Size | 200 µg |
Source / Host | human |
Species Reactivity | bacteria |
Storage | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
Substrate / Buffer | PBS with 0.02% Proclin 300. |
UniProt Number | P10845 |
Product Page Updated | 2024-03-25T11:22:07.969Z |