Article No
Ab00217-26.0-BT
Specifications
| Accession Number | P01730 |
| Additional Information | This is a recombinant monoclonal antibody. |
| Application | WB, IP, IF, IHC, FC |
| Article No | Ab00217-26.0-BT |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | MT310 |
| Clone Type | recombinant |
| Conjugation | Unconjugated |
| Description | Anti-CD4 [MT310] |
| Supplier | Absolute Antibody |
| Format | Purified |
| Isotype | IgG1 |
| Notes | mt310 can inhibit gp120 binding to CD4, which blocks HIV infectivity of CD4+ T lymphocytes, as well as the binding of MHCII, which results in the block of T-cell activation, possibly leading to the induction of anergy. Antibody binding to CD4 additionally causes the induction of GM-CSF, TNF-α (only after 20 h) and IL-10. |
| Alias Names | Leu3/T3; T-cell differentiation antigen; Ly-4; L3T4; T-cell surface antigen T4/Leu-3 |
| Product Type | Antibodies Primary |
| Purification | Purified |
| Shipping Information | Wet Ice |
| Size | 1 mg |
| Source / Host | monkey |
| Species Reactivity | human, monkey |
| Storage | Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C. |
| Substrate / Buffer | PBS only. |
| Technical Specifications | This chimeric rhesus macaque antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| UniProt Number | P01730 |
| Product Page Updated | 2024-03-25T11:22:07.969Z |
